In recent years, Bolivia and Ecuador have been the scene of radical ontological turns induced by processes of building new political constitutions. For the fi rst time, collectives with animist, analogist and naturalist modes of identifi cation had to negotiate and conciliate their «worlds» and «natures». In this article we explore the mediating role of the nature-Pachamama in the Bolivian context and its power to integrate and reassemble successfully diverging perspectives and notions of being in a new national constitution.